Arterial–Mixed Venous O₂ Difference Calculator

Calculates C(a-v)O₂ from arterial and mixed venous oxygen content.

Inputs

Color mode links each input to the matching equation term and solving arithmetic.

Equation and Work

Equation:
Solving steps:
C(a-v)O₂
—
vol%
Interpretation
—
4–5 vol% target
Extraction hint
—
relative
Normal/reference: 4–5 vol% for healthy or critically ill patients with cardiopulmonary compensation.

Clinical Significance

C(a-v)O₂ is the arterial minus mixed venous oxygen content difference: CaO₂ − CvO₂.

This difference reflects the balance among oxygen delivery, oxygen consumption, and cardiac output. A higher value often suggests increased extraction or lower cardiac output; a lower value can occur with high output states or impaired extraction.

Calculator output should be interpreted with the patient’s condition, measurement quality, and local clinical policy.

References (APA 7th Edition)

  1. Chang, D. W. (2020). Respiratory Care Calculations (Revised 4th ed.). Jones & Bartlett Learning. Formula content adapted from the uploaded text/reference packet.