Oxygen Index Calculator

Calculator for oxygen index \( OI = \frac{FiO_2 \times MAP \times 100}{PaO_2} \), used to quantify oxygenation difficulty and severity of hypoxemic respiratory failure.

Oxygenation Inputs

Oxygen Index Output

Formula (display):
FiO2 conversion:
Given:
FiO2 fraction
MAP cmH2O
PaO2 mmHg
Compute:
Current oxygen index
0.0
OI units
Interpretation:

Oxygen Index Visualizer

Oxygen Index Scale
Higher values reflect more severe oxygenation difficulty
Lower severity Higher severity
05102040

Clinical Significance

Oxygen index incorporates inspired oxygen concentration, mean airway pressure, and arterial oxygen tension into a single value. It is used to describe the degree of support required to achieve a given PaO2.

A rising oxygen index indicates that progressively greater FiO2 and airway pressure support are required to maintain arterial oxygenation. Lower values generally reflect more efficient oxygen transfer at lower support settings.

As a general teaching framework, oxygen index values below about 5 are often relatively reassuring, 5 to 10 suggest increased support needs, 10 to 20 reflect significant oxygenation impairment, and values above 20 indicate severe oxygenation difficulty. Specific clinical thresholds vary by population and institutional use.

Oxygen index should be interpreted with the ventilator mode, lung recruitment state, hemodynamics, disease process, and the broader clinical picture. It is especially useful for trending severity over time rather than as a stand-alone decision point.

References (APA 7th Edition)

  1. ARDS Definition Task Force, Ranieri, V. M., Rubenfeld, G. D., Thompson, B. T., Ferguson, N. D., Caldwell, E., Fan, E., Camporota, L., & Slutsky, A. S. (2012). Acute respiratory distress syndrome: The Berlin definition. JAMA, 307(23), 2526–2533. https://doi.org/10.1001/jama.2012.5669
  2. Pediatric Acute Lung Injury Consensus Conference Group. (2015). Pediatric acute respiratory distress syndrome: Consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference. Pediatric Critical Care Medicine, 16(5 Suppl 1), S23–S40.
  3. Khemani, R. G., Smith, L. S., Zimmerman, J. J., & Erickson, S. (2015). Pediatric acute respiratory distress syndrome: Definition, incidence, and epidemiology. Pediatric Critical Care Medicine, 16(5 Suppl 1), S23–S40.
  4. Marino, P. L. (2014). The ICU book (4th ed.). Wolters Kluwer.
  5. West, J. B., & Luks, A. M. (2021). West’s respiratory physiology: The essentials (11th ed.). Wolters Kluwer.